Epithalon
Product Overview
Epithalon (Epitalon) is a synthetic tetrapeptide derived from the pineal gland extract Epithalamin. This bioregulatory peptide has been extensively studied for its role in circadian rhythm regulation, telomerase activity, and cellular ageing processes. The compound represents a key research tool in gerontology and chronobiology studies.
Molecular Specifications
- Molecular Formula: C14H22N4O9
- Molecular Weight: 390.35 Da
- Sequence: Ala-Glu-Asp-Gly
- Purity: ≥98% (HPLC verified)
- Appearance: White lyophilised powder
- Solubility: Highly soluble in water and physiological buffers
Structural Characteristics
Epithalon is a short tetrapeptide with a simple linear structure containing acidic residues (glutamic acid and aspartic acid) that contribute to its water solubility and biological activity. The peptide's small size allows for efficient cellular uptake and distribution in research applications.
Research Applications
This compound is utilised in various research contexts investigating:
- Telomerase enzyme activity and telomere length regulation
- Circadian rhythm mechanisms and pineal gland function
- Cellular senescence and ageing pathway analysis
- Melatonin synthesis and regulation studies
- Neuroendocrine system research
- Longevity and lifespan extension mechanisms
Storage & Handling
- Storage Temperature: -20°C (lyophilised), 2-8°C (reconstituted, short-term)
- Stability: 24 months lyophilised, 30 days reconstituted at 2-8°C
- Reconstitution: Use sterile water or physiological saline
- Light Sensitivity: Store in dark conditions to prevent degradation
Quality Assurance
Each batch undergoes comprehensive analytical testing including HPLC purity analysis, mass spectrometry verification, amino acid analysis, and endotoxin testing. Certificate of Analysis provided with each shipment.
For research purposes only. Not for human consumption or therapeutic use.
