GHK-CU
Product Overview
GHK-CU (Glycyl-L-Histidyl-L-Lysine-Copper) is a naturally occurring copper-binding tripeptide complex found in human plasma, saliva, and urine. This bioactive compound has been extensively studied for its role in tissue remodelling, wound healing, and cellular regeneration processes.
Molecular Specifications
- Molecular Formula: C14H24CuN6O4
- Molecular Weight: 403.93 Da
- Sequence: Gly-His-Lys complexed with Cu²⁺
- Purity: ≥98% (HPLC verified)
- Appearance: Blue crystalline powder
- Solubility: Highly soluble in water and physiological buffers
Structural Characteristics
The copper ion in GHK-CU is coordinated through the amino nitrogen of glycine, the imidazole nitrogen of histidine, and the amino group of lysine, forming a stable square-planar complex. This unique coordination geometry is essential for its biological activity and stability in aqueous solutions.
Research Applications
This compound is utilised in various research contexts investigating:
- Collagen synthesis and extracellular matrix remodelling
- Wound healing and tissue repair mechanisms
- Antioxidant enzyme activity and oxidative stress
- Angiogenesis and vascular development
- Cellular proliferation and differentiation studies
- Matrix metalloproteinase regulation
Storage & Handling
- Storage Temperature: 2-8°C (powder), protect from light
- Stability: 24 months when stored properly
- Reconstitution: Use distilled water or appropriate buffer
- pH Stability: Optimal stability at physiological pH (7.0-7.4)
Quality Assurance
Each batch undergoes comprehensive analytical testing including HPLC purity analysis, ICP-MS copper content verification, mass spectrometry confirmation, and endotoxin testing. Certificate of Analysis provided with each shipment.
For research purposes only. Not for human consumption or therapeutic use.
