Semax
Product Overview
Semax is a synthetic heptapeptide derived from the adrenocorticotropic hormone (ACTH) fragment ACTH(4-10). This neuropeptide has been extensively studied for its nootropic properties and neuroprotective effects. Originally developed in Russia, Semax represents a significant advancement in peptide-based cognitive enhancement research.
Molecular Specifications
- Molecular Formula: C37H51N9O10S
- Molecular Weight: 813.93 Da
- Sequence: Met-Glu-His-Phe-Pro-Gly-Pro
- Purity: ≥98% (HPLC verified)
- Appearance: White lyophilised powder
- Solubility: Soluble in sterile water and physiological buffers
Structural Characteristics
Semax contains a methionine residue at the N-terminus and incorporates the core ACTH(4-7) sequence (Met-Glu-His-Phe) followed by a Pro-Gly-Pro extension. This structural modification enhances metabolic stability and prolongs biological activity compared to the parent ACTH fragment.
Research Applications
This compound is utilised in various research contexts investigating:
- Cognitive function and memory formation mechanisms
- Neuroprotective pathways and brain-derived neurotrophic factor (BDNF) regulation
- Stress response and adaptation mechanisms
- Neurotransmitter system modulation studies
- Cerebrovascular function and blood-brain barrier research
- Learning and memory consolidation processes
Storage & Handling
- Storage Temperature: -20°C (lyophilised), 2-8°C (reconstituted, short-term)
- Stability: 24 months lyophilised, 30 days reconstituted at 2-8°C
- Reconstitution: Use sterile water or bacteriostatic water
- pH Stability: Stable at physiological pH (7.0-7.4)
Quality Assurance
Each batch undergoes comprehensive analytical testing including HPLC purity analysis, mass spectrometry verification, amino acid analysis, and endotoxin testing. Certificate of Analysis provided with each shipment.
For research purposes only. Not for human consumption or therapeutic use.
